The general objective of this research is to learn about the process of integration between transpersonal psychotherapy and ayahuasca sessions in retreat centers in Peru. It is a crosssectional field research that employed a qualitative research approach of phenomenologicalhermeneutic type with the purpose of investigating the phenomenon by analyzing the key informants' own words. The data were collected through focused in-depth interviews with experts in the research topic who gave their consent for their names to be expressly mentioned in the research. The results made it possible to identify the psychotherapeutic approaches used in retreat centers in Peru where transpersonal psychotherapy and ayahuasca sessions are integrated. It was also possible to describe the techniques used by the therapists in the ayahuasca sessions. In addition, it was possible to detail the favorable and adverse phenomena that occur in the process of integration between transpersonal psychotherapy and ayahuasca sessions. The conclusion reached is that in Peru there are retreat centers that coherently integrate transpersonal psychotherapy and ayahuasca sessions. It was also concluded that a very important factor in the success of ayahuasca therapy is the so-called integrative psychotherapy.